The Wellnezz Concept Co
No. 001Botanical

Withania somnifera

Root

Botanical

Ashwagandha

A root used in Ayurveda as a rasayana, a class of herbs traditionally given to support strength and recovery.

Botanical name
Withania somnifera
Also known as
Indian winter cherry
Part used
Root
Evidence
Systematic review evidence Evidence level 5 of 5
Key compounds
Withanolides, including withaferin A and withanolide D, together with alkaloids and saponins.

In tradition

Classical Ayurvedic texts describe ashwagandha as a rejuvenative, traditionally given during convalescence and in older age.

In research

Its withanolides are the constituents studied most often. Clinical trials have examined its effects on perceived stress, sleep quality and physical performance.

Strength of evidence

Systematic review evidence Evidence level 5 of 5

Several trials pooled and appraised together. How we grade evidence.

What we know

  • Several randomised trials, pooled in meta-analyses, show short-term reductions in self-reported stress and anxiety with standardised root extracts.

What we do not know yet

  • Long-term effects beyond about three months, the best extract and dose, and how often adverse reactions occur.

Safety and cautions

Usually well tolerated in trials. Rare cases of liver injury have been reported. Not advised in pregnancy. Seek advice if you have thyroid, autoimmune or liver disease, or take sedatives, thyroid medicines or immunosuppressants.

Regulatory notes

Several European food safety authorities have reviewed ashwagandha. Denmark restricted it in food supplements in 2023, while other countries continue to permit it.

Ingredient pages summarise traditional use and the direction of published research for education. They are not claims about any product and are not medical advice.

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