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Systematic review and meta-analysis Evidence level 5 of 5 Supportive

Ashwagandha for stress and anxiety: a meta-analysis of randomised trials

The question: What does the pooled evidence say about ashwagandha and anxiety?

Study type
Systematic review and meta-analysis
Population
Adults in randomised controlled trials of ashwagandha
Intervention
Ashwagandha supplementation at varying doses
Compared with
Placebo
Duration
Trials of several weeks
Published
Phytotherapy Research, 2022

What was measured

Pooled changes in anxiety and stress scores.

What was found

Pooled analysis found reductions in anxiety and stress scores with ashwagandha compared with placebo.

Limitations

The included trials were mostly small and short, with different extracts and doses. Reviewers noted that results were sensitive to individual trials.

What it means

The direction of evidence is consistent, but the certainty is moderate at best. Larger, longer and independent trials are still needed.

Source

Akhgarjand C, Asoudeh F, Bagheri A, et al. Does Ashwagandha supplementation have a beneficial effect on the management of anxiety and stress? A systematic review and meta-analysis of randomized controlled trials. Phytother Res. 2022;36(11):4115-4124.

Read the original (DOI 10.1002/ptr.7598) · Source verified 8 October 2026

Study summaries describe published research for education. They are not claims about any product and are not medical advice.

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