Melatonin

The hormone that tells the body it is night.

Evidence: Systematic review evidence Evidence level 5 of 5
Body systems: Vitality and immunity

In research

Melatonin is released by the pineal gland in darkness and helps set the sleep and wake cycle.

Strength of evidence

Systematic review evidence

Several trials pooled and appraised together. How we grade evidence.

What we know

A Cochrane review found that melatonin taken near bedtime at the destination reduces jet lag.

What we do not know yet

Long-term effects of regular use.

Safety and cautions

Can cause next-day drowsiness. People with epilepsy, or taking warfarin, should seek advice. Avoid driving if drowsy.

Evidence

Research and answers

Appraised research and plain-language answers that involve Melatonin.

Systematic review and meta-analysis Supportive

Melatonin for the prevention and treatment of jet lag

One of the better-supported uses of melatonin, provided the timing is right. People with epilepsy or taking warfarin should seek advice first.

Cochrane Database of Systematic Reviews, 2002 · Melatonin

QuestionVitality and immunity

What does too little sleep do to the body?

In the short term, poor sleep affects mood, concentration, appetite and blood sugar.

Where you will find it

Products that contain it

Ceptomin A complete daily nutritional foundation. Film-coated tablet · 2 mg

Often found alongside

The full atlas

Aloe veraAloe barbadensis AmlaEmblica officinalis ArjunaTerminalia arjuna AshwagandhaWithania somnifera BiotinVitamin CalciumMineral

Ingredient pages summarise traditional use and the direction of published research for education. They are not claims about any product and are not medical advice.

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